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Accidental plant poisoning with
Colchicum autumnale: report of two cases.
Brncic N,
Viskovic I, Peric R, Dirlic A, Vitezic D, Cuculic
D.
Department of Infectious Diseases, Rijeka University
Hospital, Croatia. nada.brncic@medri.hr
Colchicine poisoning is a
rare but serious and potentially fatal event, which results from food
poisoning or overdose with drugs containing colchicine, with no
currently available antidote. We report two cases of plant poisoning
with Colchicum autumnale, in which the patients had identical initial
symptoms but developed extremely different clinical courses. One patient
recovered after only moderate gastroenteritis and liver injury, whereas
the other died of rapid progressive multiple organ failure 52 h after
the plant ingestion. We recommend that all patients suspected of
colchicine intoxication due to its unpredictable outcome should be
managed according to the principles of intensive care, irrespective of
the actual degree of poisoning.
Publication Types:
PMID: 11740853 [PubMed - indexed for
MEDLINE]
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